Biography
Dr. Gatha Thacker is an academic and researcher specializing in molecular oncology and cancer biology.
Ph.D from CSIR-Central Drug Research Institute, Lucknow (2014-2019), PostDoc. from University of Pennsylvania & University of Miami, USA (2019-2024), Staff Scientist at The Wistar Institute, Philadelphia, USA (2024-2026)
Research Interests
My research interests focus on cancer immunology and translational biology, particularly understanding the molecular mechanisms underlying tumor progression, immune escape, metastasis, and therapeutic resistance. I am interested in integrating multi-omics tumor profiling, patient-derived xenograft (PDX) models, and iPSC-based immune modeling to identify and validate neo-antigenic targets and study antigen-specific immune responses.My work also explores tumor microenvironment heterogeneity, immune cell crosstalk, aberrant signaling pathways, and mechanisms of immune exhaustion and reprogramming. My long-term goal is to develop autologous regenerative immune-tumor platforms that support precision immunotherapy design and enable improved diagnostic and therapeutic strategies for solid tumors.