Biography
Dr. Yidong Bai's lab is interested in a comprehensive understanding of mitochondrial function at the molecular, cellular, tissue, and animal levels. Mitochondria play a central role in cellular energy and also regulate apoptosis, signal transduction and cell growth. Mitochondrial defects have been reported in a wide range of conditions, such as diabetes, neurodegenerative diseases, cancers, and aging.
The central theme in the laboratory is to investigate the regulatory mechanisms working in mitochondria and the role of mitochondria in regulating various cellular pathways.
In particular, the lab is interested in the dynamics of the machinery for oxidative phosphorylation, the role of mitochondrial dysfunction in human diseases including cancer and aging process. Various approaches are also explored in restoring the mitochondrial function in cells with mitochondrial deficiency.
Research Interests
Cancer, Diabetes & Kidney Health, Infectious Disease, Longevity & Aging, Neuroscience